INRiM has been collaborating with aerospace agencies and industries for many years, contributing to developing satellites, sensors, telescopes, space engines, and stabilization technologies by accurate measurements. In particular, it has contributed to the implementation of Galileo, the European satellite navigation system.

Today, the Institute provides support for space missions, participates in the Copernicus programme, the most advanced Earth observation system, and verifies the functioning of Galileo atomic clocks.